Application
Western blot analysis of REEP4 in human lung tissue lysate with REEP4 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Product Name | REEP4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | REEP4 Antibody: PP432, C8orf20, PP432, Receptor expression-enhancing protein 4 |
| Product description | REEP4 Antibody: Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.1) Saito H, Kubota M, Roberts RW, et al. RTP family members induce functional expression of mammalian odorant receptors. Cell2004; 119:679-91. |
| Immunogen | REEP4 antibody was raised against a 17 amino acid synthetic peptide near the center of human REEP4. The immunogen is located within amino acids 160 - 210 of REEP4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| REEP4 antibody can be used for detection of REEP4 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | REEP4 |
|---|---|
| Alternative Names | REEP4 Antibody: PP432 C8orf20 PP432 Receptor expression-enhancing protein 4 |
Application
Western blot analysis of REEP4 in human lung tissue lysate with REEP4 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
|---|---|
| Application Notes | REEP4 antibody can be used for detection of REEP4 by Western blot at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | REEP4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | REEP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
