DNA-binding protein RFX2, Regulatory factor X 2, RFX2
Product description
This gene is a member of the regulatory factor X gene
family, which encodes transcription factors that contain a
highly-conserved winged helix DNA binding domain. The protein
encoded by this gene is structurally related to regulatory factors
X1, X3, X4, and X5. It is a transcriptional activator that can bind
DNA as a monomer or as a heterodimer with other RFX family members.
This protein can bind to cis elements in the promoter of the IL-5
receptor alpha gene. Two transcript variants encoding different
isoforms have been described for this gene, and both variants
utilize alternative polyadenylation sites.1) Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) :
Immunogen
This RFX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human RFX2.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.