Application
Western blot analysis in WiDr cell line lysates (35ug/lane).| Product Name | RFXANK Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DNA-binding protein RFXANK, Ankyrin repeat family A protein 1, Regulatory factor X subunit B, RFX-B, Regulatory factor X-associated ankyrin-containing protein, RFXANK, ANKRA1, RFXB |
| Product description | Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.1) Garvie, C.W., et al. Biochim. Biophys. Acta 1779(12):797-804(2008) |
| Immunogen | This RFXANK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-123 amino acids from the Central region of human RFXANK. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RFXANK |
|---|---|
| Alternative Names | DNA-binding protein RFXANK Ankyrin repeat family A protein 1 Regulatory factor X subunit B RFX-B Regulatory factor X-associated ankyrin-containing protein RFXANK ANKRA1 RFXB |
| Molecular Weight(MW) | 28 kDa |
Application
Western blot analysis in WiDr cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
