RGP1 Antibody: KIAA0258, KIAA0258, Retrograde Golgi transport protein RGP1 homolog
Product description
RGP1 Antibody: Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, a protein that forms a tight complex with RIC1. This complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 is localized to the Golgi and is thought to be a potential Golgi recycling factor. Rgp1 yeast mutants exhibit defects in retrograde trafficking similar to those seen in yeast with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells to that seen in yeast.1) Siniossoglou S, Peak-Chew SY, and Pelham HRB. Ric1p and Rgp1 form a complex that catalyzes nucleotide exchange on Ypt6p. EMBO J.2000; 19:4885-94.
Immunogen
RGP1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of the human RGP1. The immunogen is located within amino acids 50 - 100 of RGP1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
RGP1 antibody can be used for detection of RGP1 by Western blot at 1 - 2 μg/mL.:
Western blot analysis of RGP1 in human heart tissue lysate with RGP1 antibody at (A) 1 and (B) 2 μg/mL.
Positive Control
1) Cat. No. 1301 - Human Heart Tissue Lysate
Application Notes
RGP1 antibody can be used for detection of RGP1 by Western blot at 1 - 2 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
RGP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
RGP1 Antibody is supplied in PBS containing 0.02% sodium azide.