Application
Western blot analysis of RGPD5 in human thymus tissue lysate with RGPD5 antibody at 1 μg/mL in (A) the absence and (B) the presense of blocking peptide.| Product Name | RGPD5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGPD5 Antibody: BS63, RGP5, BS-63, HEL161, RANBP2L1, RGP7, RGPD7, RGPD6, RANBP2L2, RGP6, Sperm membrane protein BS-63, RanBP2L1 |
| Product description | RGPD5 Antibody: The RANBP2-like and GRIP domain containing 5 protein (RGPD5) has high similarity to RANBP2, a large RAN-binding protein localized at the cytoplasmic side of the nuclear pore complex. The gene coding for RGPD5 is thought to have arisen from a gene duplication event of RANBP2 as these highly homologous genes are located close to each other at chromosome 2q11-q12. RGPD5 was identified as an HIV dependency factor (HDF), suggesting that RGPD5 may be an important drug target in HIV treatment. At least two isoforms of RGPD5 are known to exist, of which the shorter isoform is expressed primarily in testis, while the longer of the two is expressed at low levels in a number of somatic tissues.1) Nothwang HG, Rensing C, Kubler M, et al. Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on chromosome 2q11-q12. Genomics1998; 47:383-92. |
| Immunogen | RGPD5 antibody was raised against a 23 amino acid synthetic peptide from near the center of human RGPD5. The immunogen is located within amino acids 1130 - 1180 of RGPD5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RGPD5 |
|---|---|
| Alternative Names | RGPD5 Antibody: BS63 RGP5 BS-63 HEL161 RANBP2L1 RGP7 RGPD7 RGPD6 RANBP2L2 RGP6 Sperm membrane protein BS-63 RanBP2L1 |
Application
Western blot analysis of RGPD5 in human thymus tissue lysate with RGPD5 antibody at 1 μg/mL in (A) the absence and (B) the presense of blocking peptide.| Positive Control | 1) Cat. No. 1314 - Human Thymus Tissue Lysate |
|---|---|
| Application Notes | RGPD5 antibody can be used for detection of RGPD5 by Western blot at 1 μg/mL.: |
| Form | Liquid |
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| Storage Instructions | RGPD5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | RGPD5 Antibody is supplied in PBS containing 0.02% sodium azide. |
