The protein encoded by this gene belongs to the RGS
(regulator of G protein signaling) family. Members of the RGS
family act as GTPase-activating proteins on the alpha subunits of
heterotrimeric, signal-transducing G proteins. This protein
inhibits signal transduction by increasing the GTPase activity of G
protein alpha subunits, thereby driving them into their inactive
GDP-bound form. Alternative splicing occurs at this locus and two
transcript variants encoding distinct isoforms have been
identified.1) Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Immunogen
This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.