| Product Name |
Rift Valley Fever Virus Antibody |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
Rift Valley Fever Virus Antibody: Envelope glycoprotein, M polyprotein, GP |
| Product description |
Rift Valley Fever Virus Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes. During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity. The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins.1) Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY. |
| Immunogen |
RVF virus antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the RVF virus. The immunogen is located within amino acids 960 - 1010 of Rift Valley Fever Virus. |
