Application
Immunofluorescence of RNASET2 in SW480 cells with RNASET2 antibody at 5 μg/ml.Application
Immunocytochemistry of RNASET2 in SW480 cells with RNASET2 antibody at 2.5 μg/ml.Application
Western blot analysis of RNASET2 in SW480 cell lysate with RNASET2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | RNASET2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RNASET2 Antibody: RNASE6PL, bA514O12.3, RNASE6PL, Ribonuclease T2, Ribonuclease 6 |
| Product description | RNASET2 Antibody: RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.1) Acquati F, Morelli C, Cinquetti R, et al. Cloning and characterization of a senescence inducing and class II tumor suppressor gene in ovarian carcinoma at chromosome region 6q27. Oncogene 2001; 20:980-8. |
| Immunogen | RNASET2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human RNASET2. The immunogen is located within the last 50 amino acids of RNASET2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCIFWB |
| RNASET2 antibody can be used for detection of FOXRED2 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RNASET2 |
|---|---|
| Alternative Names | RNASET2 Antibody: RNASE6PL bA514O12.3 RNASE6PL Ribonuclease T2 Ribonuclease 6 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig: (100%) |
Application
Immunofluorescence of RNASET2 in SW480 cells with RNASET2 antibody at 5 μg/ml.
Application
Immunocytochemistry of RNASET2 in SW480 cells with RNASET2 antibody at 2.5 μg/ml.
Application
Western blot analysis of RNASET2 in SW480 cell lysate with RNASET2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1221 - SW480 Cell Lysate |
|---|---|
| Application Notes | RNASET2 antibody can be used for detection of FOXRED2 by Western blot at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | RNASET2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | RNASET2 Antibody is supplied in PBS containing 0.02% sodium azide. |
