This gene encodes a type I integral membrane protein found
only in the rough endoplasmic reticulum. The encoded protein is
part of an N-oligosaccharyl transferase complex that links high
mannose oligosaccharides to asparagine residues found in the
Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This
protein forms part of the regulatory subunit of the 26S proteasome
and may mediate binding of ubiquitin-like domains to this
proteasome.1) Ruiz-Canada, C., et al. Cell 136(2):272-283(2009)
Immunogen
This RPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-587 amino acids from the C-terminal region of human RPN1.
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.