Analysis of cDNA clones indicates that ribosome binding
protein 1 may exist in different forms due to removal of tandem
repeats, or partial intraexonic splicing of RRBP1. The form
presented here is lacking the canine p180 ribosome-binding domain,
NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in
other forms that haven't been fully characterized. RRBP1 has been
excluded as a candidate gene in the cause of Alagille syndrome.
Alternate splicing results in multiple transcript variants.1) Ueno, T., et al. J. Biol. Chem. 285(39):29941-29950(2010)
Immunogen
This RRBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1327-1355 amino acids from the C-terminal region of human RRBP1.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.