Application
RSK4 Antibody is used to detect RSK4 in primate brain tissue lysate (lane 2).Application
RSK4 Antibody (N-term) is used to detect RSK4 in 7 different cell lines. Data courtesy of Dr. Yuan Sun, Hormel Institute, University of Minnesota.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.| Product Name | RSK4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Ribosomal protein S6 kinase alpha-6, S6K-alpha-6, 90 kDa ribosomal protein S6 kinase 6, p90-RSK 6, p90RSK6, Ribosomal S6 kinase 4, RSK-4, pp90RSK4, RPS6KA6, RSK4 |
| Product description | Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).1) Yntema, H.G., et al., Genomics 62(3):332-343 (1999). |
| Immunogen | This RSK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-45 amino acids from the N-terminal region of human RSK4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
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| Species Reactivity | HumanMonkey |
| Concentration | 1mg/ml |
| Gene Symbol | RPS6KA6 |
|---|---|
| Alternative Names | Ribosomal protein S6 kinase alpha-6 S6K-alpha-6 90 kDa ribosomal protein S6 kinase 6 p90-RSK 6 p90RSK6 Ribosomal S6 kinase 4 RSK-4 pp90RSK4 RPS6KA6 RSK4 |
| Molecular Weight(MW) | 84 kDa |
Application
RSK4 Antibody is used to detect RSK4 in primate brain tissue lysate (lane 2).
Application
RSK4 Antibody (N-term) is used to detect RSK4 in 7 different cell lines. Data courtesy of Dr. Yuan Sun, Hormel Institute, University of Minnesota.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
