Application
Antibody used in WB on Human Brain at 0.2-1 ug/ml.| Product Name | SAC Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SAC, HCA2, RP1-313L4.2, SACI, SAC, Sacy |
| Product description | SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Schmid, A., (2007) J. Gen. Physiol. 130 (1), 99-109. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAC. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| SAC antibody can be used for detection of SAC by ELISA at 1:62500. SAC antibody can be used for detection of SAC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADCY10 |
|---|---|
| Alternative Names | SAC HCA2 RP1-313L4.2 SACI SAC Sacy |
| Molecular Weight(MW) | 187 kDa |
Application
Antibody used in WB on Human Brain at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10123 - Fetal Brain Tissue Lysate |
|---|---|
| Application Notes | SAC antibody can be used for detection of SAC by ELISA at 1:62500. SAC antibody can be used for detection of SAC by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store SAC antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
