Histone acetylation plays a key role in the regulation of
eukaryotic gene expression. Histone acetylation and deacetylation
are catalyzed by multisubunit complexes. The protein encoded by
this gene is a component of the histone deacetylase complex, which
includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other
polypeptides. This complex is active in deacetylating core histone
octamers, but inactive in deacetylating nucleosomal histones. A
pseudogene of this gene is located on chromosome 3. [provided by
RefSeq].1) Brandt, S., et al. Int. J. Biochem. Cell Biol. 42(9):1472-1481(2010)
Immunogen
This SAP30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human SAP30.
Western blot analysis of lysate from human spleen tissue lysate, using SAP30 Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.