SAPAP4 Antibody: SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies.1) SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J. Biol. Chem.1997; 272:11943-51.
Immunogen
SAPAP4 antibody was raised against a 13 amino acid synthetic peptide from near the center of human SAPAP4. The immunogen is located within amino acids 610 - 660 of SAPAP4.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
SAPAP4 antibody can be used for detection of SAPAP4 by Western blot at 1 μg/mL.:
Western blot analysis of SAPAP4 in SK-N-SH cell lysate with SAPAP4 antibody at 1 μg/mL.
Positive Control
1) Cat. No. 1220 - SK-N-SH Cell Lysate
Application Notes
SAPAP4 antibody can be used for detection of SAPAP4 by Western blot at 1 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
SAPAP4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
SAPAP4 Antibody is supplied in PBS containing 0.02% sodium azide.