Secretoglobin family 1D member 2, Lipophilin-B, SCGB1D2, LIPHB, LPNB
Product description
The protein encoded by this gene is a member of the
lipophilin subfamily, part of the uteroglobin superfamily, and is
an ortholog of prostatein, the major secretory glycoprotein of the
rat ventral prostate gland. Lipophilin gene products are widely
expressed in normal tissues, especially in endocrine-responsive
organs. Assuming that human lipophilins are the functional
counterparts of prostatein, they may be transcriptionally regulated
by steroid hormones, with the ability to bind androgens, other
steroids and possibly bind and concentrate estramustine, a
chemotherapeutic agent widely used for prostate cancer. Although
the gene has been reported to be on chromosome 10, this sequence
appears to be from a cluster of genes on chromosome 11 that
includes mammaglobin 2.1) Sjodin, A., et al. Anticancer Res. 28 (3A), 1493-1498 (2008) :
Immunogen
This SCGB1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the Central region of human SCGB1D2.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.