Cytochrome c oxidase (COX) catalyzes the transfer of
electrons from cytochrome c to molecular oxygen, which helps to
maintain the proton gradient across the inner mitochondrial
membrane that is necessary for aerobic ATP production. Human COX is
a multimeric protein complex that requires several assembly
factors; this gene encodes one of the COX asembly factors. The
encoded protein is a metallochaperone that is involved in the
biogenesis of cytochrome c oxidase subunit II. Mutations in this
gene are associated with fatal infantile encephalocardiomyopathy.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This SCO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human SCO2.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.