Application
Immunohistochemistry of SDPR in spleen tissue with SDPR antibody at 5 μg/ml.Application
Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 μg/ml.Application
Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL| Product Name | SDPR Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | SDPR Antibody: The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP were down regulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.1) Gustincich S, Vatta P, Goruppi S, et al. The human serum deprivation response gene (SDPR) maps to 2q32-q33 and codes for a phosphatidylserine-binding protein. Genomics 1999; 57:120-9. |
| Immunogen | Rabbit polyclonal SDPR antibody was raised against an 18 amino acid peptide near the amino terminus of human SDPR. The immunogen is located within the first 50 amino acids of SDPR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SDPR |
|---|---|
| Alternative Names | SDPR Antibody: SDR CAVIN2 PS-p68 cavin-2 Serum deprivation-response protein Cavin-2 |
| Molecular Weight(MW) | Predicted: 22, 33, 43 kDa kDa Observed: 30 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
| Tissue Specificity | It is predicted to not cross-react with other members of the cavin family. |
Application
Immunohistochemistry of SDPR in spleen tissue with SDPR antibody at 5 μg/ml.
Application
Immunofluorescence of SDPR in human spleen tissue with SDPR antibody at 20 μg/ml.
Application
Western blot analysis of SDPR in HeLa cell lysate with SDPR antibody at (A) 1 and (B) 2 μg/mL| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | SDPR antibody can be used for detection of SDPR by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | SDPR antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SDPR Antibody is supplied in PBS containing 0.02% sodium azide. |
