The protein encoded by this gene is similar to yeast Sec31
protein. Yeast Sec31 protein is known to be a component of the
COPII protein complex which is responsible for vesicle budding from
endoplasmic reticulum (ER). This protein was found to colocalize
with SEC13, one of the other components of COPII , in the
subcellular structures corresponding to the vesicle transport
function. An immunodepletion experiment confirmed that this protein
is required for ER-Golgi transport. Alternative splicing results in
multiple transcript variants encoding different isoforms. [provided
by RefSeq].1) Rose, J. Phd, et al. Mol. Med. (2010) In press :
Immunogen
This SEC31A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from the Central region of human SEC31A.
Western blot analysis in mouse lung tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.