This gene encodes a selenoprotein, which contains a
selenocysteine (Sec) residue at its active site. The selenocysteine
is encoded by the UGA codon that normally signals translation
termination. The 3' UTR of selenoprotein genes have a common
stem-loop structure, the sec insertion sequence (SECIS), that is
necessary for the recognition of UGA as a Sec codon rather than as
a stop signal. This gene is expressed in a variety of tissues, and
the protein is localized to the perinuclear structures. [provided
by RefSeq].1) Korotkov, K.V., et al. Mol. Cell. Biol. 22(5):1402-1411(2002)
Immunogen
This SELM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human SELM.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.