Septins, such as SEPT12, are conserved GTP-binding
proteins that function as dynamic, regulatable scaffolds for the
recruitment of other proteins. They are involved in membrane
dynamics, vesicle trafficking, apoptosis, and cytoskeleton
remodeling, as well as infection, neurodegeneration, and neoplasia
(Hall et al., 2005 [PubMed 15915442]).1) Lin, Y.H., et al. Am. J. Pathol. 174(5):1857-1868(2009)
Immunogen
This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.