This gene is a member of the septin family of GTPases.
Members of this family are required for cytokinesis. One version of
pediatric acute myeloid leukemia is the result of a reciprocal
translocation between chromosomes 11 and X, with the breakpoint
associated with the genes encoding the mixed-lineage leukemia and
septin 2 proteins. This gene encodes four transcript variants
encoding three distinct isoforms. An additional transcript variant
has been identified, but its biological validity has not been
determined.1) Ding, X., et al. J. Biochem. Mol. Biol. 40(6):973-978(2007)
Immunogen
This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.