| Product Name | Sin Nombre Virus Glycoprotein 2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Sin Nombre virus (SNV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) (1). Hantavirus glycoprotein precursor (GPC) is posttranslationally cleaved into two glycoproteins G1 (Gn) and G2 (Gc). While the G1 glycoprotein is is thought to be degraded by the host autophagy machinery, and this autophagic clearance is required for efficient virus repliaction (2), no such degradation was observed for the G2 glycoprotein.1) Spiropoulou CF, Morzunov S, Feldmann H, et al. Genome structure and variability of a virus causing hantavirus pulmonary syndrome. Virology 1994; 200:715-23. |
| Immunogen | Sin Nombre virus glycoprotein 2 antibody was raised against a 16 amino acid peptide near the center of the Sin Nombre virus glycoprotein. The immunogen is located within amino acids 670 - 720 of Sin Nombre Virus Glycoprotein 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μg/ml. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SNVsMgp1 |
|---|---|
| Alternative Names | Sin Nombre Virus Glycoprotein 2 Antibody: |
| Molecular Weight(MW) | N/A |
| Application Notes | Sin Nombre virus glycoprotein 2 antibody can detect 10ng Sin Nombre virus glycoprotein 2 peptide in ELISA at 1 μg/ml. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Sin Nombre Glycoprotein 2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | Sin Nombre virus glycoprotein 2 antibody is supplied in PBS containing 0.02% sodium azide. |
