Application
Immunohistochemistry staining of SIRT5 in kidney tissue using SIRT5 Antibody.| Product Name | SIRT5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIRT5, SIR2L5, Sir2-like 5, SIR2-like protein 5, Sirtuin 5, Sirtuin type 5 |
| Product description | SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones. |
| Immunogen | A synthetic peptide corresponding to amino acids 30-46 of h SIRT5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| SIRT5 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | SIRT5 |
|---|---|
| Alternative Names | SIRT5 SIR2L5 Sir2-like 5 SIR2-like protein 5 Sirtuin 5 Sirtuin type 5 |
Application
Immunohistochemistry staining of SIRT5 in kidney tissue using SIRT5 Antibody.| Application Notes | SIRT5 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | SIRT5 antibody can be stored short term 4 ˚C. For long term storage aliquot and store at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.05% BSA, 0.05% sodium azide. |
