Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.1) Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Immunogen
This SIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-189 amino acids from the C-terminal region of human SIT1.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.