Application
Immunohistochemistry staining of SKP1 in cerebellum tissue using SKP1 Antibody.| Product Name | SKP1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SKP1, Cyclin A/CDK2-associated p19, OCP-2, OCP-II, Organ of Corti protein 2, SIII, TCEB1L, Organ of Corti protein II, p19A, SKP1A, EMC19, OCP2, p19skp1 |
| Product description | SKP1 is also known as S-phase kinase-associated protein 1A, Cyclin A/CDK2-associated protein p19, p19A, p19skp1, RNA polymerase II elongation factor-like protein, Organ of Corti protein 2, OCP-II protein, OCP-2, Transcription elongation factor B, and SIII. SKP1 is an essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, SKP1 serves as an adapter that links the F-box protein to CUL1. SKP1 interacts directly with CUL1 and F-box proteins, such as BTRC and SKP2, in the SCF complex. SKP1 also interacts with FBX29 and the cyclin A/CDK2 complex. SKP1 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1 and FBXW8 and is also a component of a E3 ubiquitin ligase complex containing UBE2D1, SIAH1, CACYBP/SIP, SKP1A, APC and TBL1X. |
| Immunogen | SKP1 antibody was raised against amino acids 152 - 163 of SKP1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| SKP1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SKP1 |
|---|---|
| Alternative Names | SKP1 Cyclin A/CDK2-associated p19 OCP-2 OCP-II Organ of Corti protein 2 SIII TCEB1L Organ of Corti protein II p19A SKP1A EMC19 OCP2 p19skp1 |
Application
Immunohistochemistry staining of SKP1 in cerebellum tissue using SKP1 Antibody.| Application Notes | SKP1 antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.: |
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| Form | Liquid |
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| Storage Instructions | Store SKP1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Contains 0.01% sodium azide |
