Application
Immunohistochemistry of SLAIN2 in human testis with SLAIN2 antibody at 5 μg/mL.| Product Name | SLAIN2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLAIN2 Antibody: KIAA1458, KIAA1458, SLAIN motif-containing protein 2 |
| Product description | SLAIN2 Antibody: SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.1) Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103. |
| Immunogen | SLAIN2 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human SLAIN2. The immunogen is located within amino acids 70 - 120 of SLAIN2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-P |
| SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLAIN2 |
|---|---|
| Alternative Names | SLAIN2 Antibody: KIAA1458 KIAA1458 SLAIN motif-containing protein 2 |
| Molecular Weight(MW) | 64 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (100%), Mouse: (93%) |
| Tissue Specificity | SLAIN2 antibody is predicted not to cross-react with SLAIN1. |
Application
Immunohistochemistry of SLAIN2 in human testis with SLAIN2 antibody at 5 μg/mL.| Positive Control | 1) Cat. No. 11-701 - Human Testis Tissue Slide |
|---|---|
| Application Notes | SLAIN2 antibody can be used for detection of SLAIN2 by immunohistochemistry at 5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SLAIN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | SLAIN2 Antibody is supplied in PBS containing 0.02% sodium azide. |
