Application
Immunohistochemistry of SLAMF1 in human colon tissue with SLAMF1 antibody at 5 μg/mL.Application
Immunofluorescence of SLAMF1 in human colon tissue with SLAMF1 antibody at 20 μg/mL.Application
Western blot analysis of SLAMF1 in rat colon tissue lysate with SLAMF1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | SLAMF1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SLAMF1 Antibody: SLAM, CD150, CDw150, SLAM, Signaling lymphocytic activation molecule |
| Product description | SLAMF1 Antibody: The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).1) Cocks BG, Chang CC, Carballido JM, et al. 1995. A novel receptor involved in T cell activation. Nature 1995; 376:260-3. |
| Immunogen | SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1. The immunogen is located within amino acids 30 - 80 of SLAMF1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLAMF1 |
|---|---|
| Alternative Names | SLAMF1 Antibody: SLAM CD150 CDw150 SLAM Signaling lymphocytic activation molecule |
| Tissue Specificity | Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members. |
Application
Immunohistochemistry of SLAMF1 in human colon tissue with SLAMF1 antibody at 5 μg/mL.
Application
Immunofluorescence of SLAMF1 in human colon tissue with SLAMF1 antibody at 20 μg/mL.
Application
Western blot analysis of SLAMF1 in rat colon tissue lysate with SLAMF1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1472 - Rat Colon Tissue Lysate |
|---|---|
| Application Notes | SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SLAMF1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | SLAMF1 Antibody is supplied in PBS containing 0.02% sodium azide. |
