Application
Immunofluorescence of Slc22A17 in rat kidney tissue tissue with Slc22A17 antibody at 20 μg/mL.Application
Immunohistochemistry of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 2.5 μg/ml.Application
Immunofluorescence of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 20 μg/ml.Application
Western blot analysis of Slc22A17 in SK-N-SH lysate with Slc22A17 antibody at 0.5 μg/mL in (A) the presence and (B) the absence of blocking peptide.| Product Name | Slc22A17 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Slc22A17 Antibody: BOCT, BOIT, 24p3R, NGALR, hBOIT, NGALR2, NGALR3, BOCT, Solute carrier family 22 member 17, 24p3 receptor |
| Product description | Slc22A17 Antibody: The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.1) Koepsell H and Endou H. The SLC22 drug transporter family. Pflugers Arch. 2004; 447:666-76. |
| Immunogen | Slc22A17 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17. The immunogen is located within the last 50 amino acids of Slc22A17. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| Slc22A17 antibody can be used for detection of Slc22A17 by Western blot at 0.5 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLC22A17 |
|---|---|
| Alternative Names | Slc22A17 Antibody: BOCT BOIT 24p3R NGALR hBOIT NGALR2 NGALR3 BOCT Solute carrier family 22 member 17 24p3 receptor |
| Molecular Weight(MW) | Predicted: 59 kDa Observed: 61 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (86%) |
Application
Immunofluorescence of Slc22A17 in rat kidney tissue tissue with Slc22A17 antibody at 20 μg/mL.
Application
Immunohistochemistry of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 2.5 μg/ml.
Application
Immunofluorescence of SLC22A17 in mouse kidney tissue with SLC22A17 antibody at 20 μg/ml.
Application
Western blot analysis of Slc22A17 in SK-N-SH lysate with Slc22A17 antibody at 0.5 μg/mL in (A) the presence and (B) the absence of blocking peptide.| Positive Control | 1) Cat. No. 1220 - SK-N-SH Cell Lysate |
|---|---|
| Application Notes | Slc22A17 antibody can be used for detection of Slc22A17 by Western blot at 0.5 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Slc22A17 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Slc22A17 Antibody is supplied in PBS containing 0.02% sodium azide. |
