SLC26A3 is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.The protein encoded by this gene is a transmembrane glycoprotein that functions as a sulfate transporter. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. Mutations in this gene have been associated with congenital chloride diarrhea. Please see the Entrez Gene record to access additional publications.1) Dorwart, M.R., (2008) J. Biol. Chem. 283 (13), 8711-8722.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC26A3.
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
Cocktail
Host Species
Rabbit
Tested Applications
ELISAWB
SLC26A3 antibody can be used for detection of SLC26A3 by ELISA at 1:312500. SLC26A3 antibody can be used for detection of SLC26A3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human Placenta lysate at 0.2-1 ug/ml.
Application
Antibody used in WB on Human HepG2.
Positive Control
1) Cat. No. 1309 - Human Placenta Lysate
Application Notes
SLC26A3 antibody can be used for detection of SLC26A3 by ELISA at 1:312500. SLC26A3 antibody can be used for detection of SLC26A3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store SLC26A3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.