Application
Western blot analysis of SLC36A2 in human stomach tissue lysate with SLC36A2 antibody at1 μg/ml.| Product Name | SLC36A2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Solute carrier family 36 (proton/amino acid symporter) member 2, proton-coupled amino acid transporter 2, PAT2, TRAMD1 |
| Product description | SLC36A2 is a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline (1,2). Both SLC36A2 and its paralog SLC36A1 are expressed in neurons, but SLC36A2 localizes to the endoplasmic reticulum and recycling endosome, while SLC36A1 is expressed in the lysosome (2). SLC36A2 is thought to contribute to neuronal transport and sequestration of amino acids such as glycine, alanine, and proline (2). Mutations in this gene are associated with iminoglycinuria and hyperglycinuria (3).1) Boll M, Foltz M, Rubio-Aliaga I, et al. Functional characterization of two novel mammalian electrogenic proton-dependent amino acid cotransporters. J. Biol. Chem. 2002; 277:22966-73. |
| Immunogen | SLC36A2 antibody was raised against a 15 amino acid peptide near the amino terminus of human SLC36A2. The immunogen is located within amino acids 30 - 80 of SLC36A2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| SLC36A2 antibody can be used for detection of SLC36A2 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLC36A2 |
|---|---|
| Alternative Names | Solute carrier family 36 (proton/amino acid symporter) member 2 proton-coupled amino acid transporter 2 PAT2 TRAMD1 |
| Molecular Weight(MW) | Predicted: 53 kDa Observed: 52 kDa |
| Tissue Specificity | SLC36A2 antibody is human specific. SLC36A2 is predicted to not cross-react with other members of the SLC36 protein family. |
Application
Western blot analysis of SLC36A2 in human stomach tissue lysate with SLC36A2 antibody at1 μg/ml.| Positive Control | 1) Cat. No. 1319 - Human Stomach Tissue Lysate |
|---|---|
| Application Notes | SLC36A2 antibody can be used for detection of SLC36A2 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SLC36A2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SLC36A2 antibody is supplied in PBS containing 0.02% sodium azide. |
