Application
Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.Application
Western blot analysis of SLC38A4 in mouse kidney tissue lysate with SLC38A4 antibody at (A) 1 and (B) 2 μg/ml.| Product Name | SLC38A4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Solute carrier family 38 member 4, sodium-coupled neutral amino acid transporter 4, SNAT4, protein associated with ABC transporters, PAAT, ATA3, NAT3 |
| Product description | SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids (1,2). The transport of cationic amino acids by SLC38A4 is sodium and pH independent, while the transport of neutral amino acids is sodium and pH dependent (2). Recent evidence suggests that SLC38A4 functions as a regulator of protein synthesis downstream of the hepatocyte nuclear factor 4a during liver development (3). It has also been suggested that SLC38A4 has ATPase activity and is critically involved in the maintenance of mitochondrial homeostasis and cell survival (4).1) Sugawara M, Nakanishi T, Fei YJ, et al. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal system. Biochim. Biophys. Acta 2000; 1509:7-13. |
| Immunogen | SLC38A4 antibody was raised against an 18 amino acid peptide from near the center of human SLC38A4. The immunogen is located within amino acids 270 - 320 of SLC38A4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| SLC38A4 antibody can be used for the detection of SLC38A4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SLC38A4 |
|---|---|
| Alternative Names | Solute carrier family 38 member 4 sodium-coupled neutral amino acid transporter 4 SNAT4 protein associated with ABC transporters PAAT ATA3 NAT3 |
| Molecular Weight(MW) | Predicted: 60 kDa Observed: 60 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rat: (71%) |
| Tissue Specificity | SLC38A4 antibody is human and mouse reactive. SLC38A4 will not cross-react with other members of the SLC38 protein family. |
Application
Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.
Application
Western blot analysis of SLC38A4 in mouse kidney tissue lysate with SLC38A4 antibody at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1405 - Mouse Kidney Tissue Lysate |
|---|---|
| Application Notes | SLC38A4 antibody can be used for the detection of SLC38A4 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SLC38A4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SLC38A4 Antibody is supplied in PBS containing 0.02% sodium azide. |
