The protein encoded by this gene is part of a complex that
relieves repressive chromatin structures, allowing the
transcriptional machinery to access its targets more effectively.
The encoded nuclear protein may also bind to and enhance the DNA
joining activity of HIV-1 integrase. This gene has been found to be
a tumor suppressor, and mutations in it have been associated with
malignant rhabdoid tumors. Two transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].1) Bakshi, R., et al. J. Cell. Physiol. 225(2):569-576(2010)
Immunogen
This SMARCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human SMARCB1.
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application
Western blot analysis in human placenta tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.