Application
Immunofluorescence of SNRPN in human spleen tissue with SNRPN antibody at 20 μg/mL.Application
Immunohistochemistry of SNRPN in human spleen tissue with SNRPN antibody at 5 μg/mL.Application
Western blot analysis of SNRPN in THP-1 cell lysate with SNRPN antibody at (A) 0.5 and (B) 1 μg/ml.| Product Name | SNRPN Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The small nuclear riboprotein-associated protein N (SNRPN) is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN plays a role in pre-mRNA processing and alternative splicing (1). SNRPN arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF) (2). Mutations or deletions in the SNRPN gene may be linked to responsible for Angelman syndrome or Prader-Willi syndrome (3).1) Ozcelik T, Leff S, Robinson W, et al. Small nuclear ribonucleoprotein polypeptide N (SNRPN), an expressed gene in the Prader-Willi syndrome critical region. Nat. Genet. 1992; 2:265-9. |
| Immunogen | SNRPN antibody was raised against a 20 amino acid peptide near the amino terminus of human SNRPN. The immunogen is located within amino acids 30 - 80 of SNRPN. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| SNRPN antibody can be used for detection of SNRPN by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SNRPN |
|---|---|
| Alternative Names | Small nuclear ribonucleoprotein-associated protein N HCERN3 PWCR RT-LI SM-D SMN SNRNP-N SNURF-SNRPN sm-N |
| Molecular Weight(MW) | Predicted: 26 kDa Observed: 25 kDa |
Application
Immunofluorescence of SNRPN in human spleen tissue with SNRPN antibody at 20 μg/mL.
Application
Immunohistochemistry of SNRPN in human spleen tissue with SNRPN antibody at 5 μg/mL.
Application
Western blot analysis of SNRPN in THP-1 cell lysate with SNRPN antibody at (A) 0.5 and (B) 1 μg/ml.| Positive Control | 1) Cat. No. 1208 - THP-1 Cell Lysate |
|---|---|
| Application Notes | SNRPN antibody can be used for detection of SNRPN by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | SNRPN antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SNRPN antibody is supplied in PBS containing 0.02% sodium azide. |
