This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular
trafficking. The encoded protein also contains a regulator of G
protein signaling (RGS) domain. Regulator of G protein signaling
family members are regulatory molecules that act as GTPase
activating proteins for G alpha subunits of heterotrimeric G
proteins. Two transcript variants encoding distinct isoforms have
been identified for this gene.1) Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Immunogen
This SNX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 580-608 amino acids from the Central region of human SNX14.
Western blot analysis in mouse testis tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.