Application
Immunofluorescence of SOGA1 in HeLa cells with SOGA1 antibody at 5 μg/mL.Application
Western blot analysis of SOGA1 in Hela cell lysate with SOGA1 antibody at (A) 1 and (B) 2 μg/ml.| Product Name | SOGA1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).1) Cowherd RB, Asmar MM, Alderman JM, et al. Adiponectin lowers glucose production by increasing SOGA. Am. J. Pathol. 2010; 177:1936-45. |
| Immunogen | SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μg/ml. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SOGA1 |
|---|---|
| Alternative Names | SOGA1 Antibody : SOGA KIAA0889 C20orf117 SOGA Protein SOGA1 SOGA family member 1 80-kDa SOGA fragment |
| Molecular Weight(MW) | Predicted: 183 kDa Observed: 200kDa |
Application
Immunofluorescence of SOGA1 in HeLa cells with SOGA1 antibody at 5 μg/mL.
Application
Western blot analysis of SOGA1 in Hela cell lysate with SOGA1 antibody at (A) 1 and (B) 2 μg/ml.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μg/ml. |
| Form | Liquid |
|---|---|
| Storage Instructions | SOGA1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | SOGA1 Antibody is supplied in PBS containing 0.02% sodium azide. |
