This gene encodes a member of the SOX (SRY-related
HMG-box) family of transcription factors involved in the regulation
of embryonic development and in the determination of the cell fate.
The encoded protein may act as a transcriptional activator after
forming a protein complex with other proteins. This protein may be
involved in brain development and function. Haploinsufficiency for
this protein may contribute to the mental retardation found in
haemoglobin H-related mental retardation (ART-16 syndrome).1) Nonaka, D. Am. J. Clin. Pathol. 131(5):731-736(2009)
Immunogen
This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.
Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.