Synovial sarcomas occur most frequently in the extremities
around large joints. More than 90% of cases have a recurrent and
specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which
the 5-prime end of the SS18 gene (MIM 600192) is fused in-frame to
the 3-prime end of the SSX1 (MIM 312820), SSX2 (MIM 300192), or
SSX4 (MIM 300326) gene. The SS18L1 gene is homologous to
SS18.1) Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Immunogen
This SS18L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-300 amino acids from the Central region of human SS18L1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.