Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Product Name | SSX4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A |
| Product description | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.1) Ayyoub, M., et al. J. Immunol. 174(8):5092-5099(2005) |
| Immunogen | This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the Central region of human SSX4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SSX4 |
|---|---|
| Alternative Names | Protein SSX4 Cancer/testis antigen 54 CT54 SSX4 SSX4A |
| Molecular Weight(MW) | 22 kDa |
Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
