Application
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.| Product Name | Stargazin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | stg, wag, waggler, AW060990, stargazer, stargazin, B230105C07Rik, B930041E13Rik, Stg, Neuronal voltage-gated calcium channel gamma-2 subunit, TARP gamma-2 |
| Product description | Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002).1) Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS,(2005) Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature 435: 1052-1058. |
| Immunogen | Peptide corresponding to amino acid residues from the C-terminal region of rat stargazin, conjugated to keyhole limpet hemocyanin (KLH). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| The antibody has been directly tested for reactivity in rat tissue. It is anticipated that the antibody will also work with mouse tissue based on the fact that this species has 100% homology with the amino acid sequence used as antigen.: |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Cacng2 |
|---|---|
| Alternative Names | stg wag waggler AW060990 stargazer stargazin B230105C07Rik B930041E13Rik Stg Neuronal voltage-gated calcium channel gamma-2 subunit TARP gamma-2 |
| Molecular Weight(MW) | 36 |
Application
Western blot of rat synaptic membrane (SPM) showing specific immunolabeling of the ~ 36k stargazin protein.| Application Notes | The antibody has been directly tested for reactivity in rat tissue. It is anticipated that the antibody will also work with mouse tissue based on the fact that this species has 100% homology with the amino acid sequence used as antigen.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stargazin antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year. |
| Storage Buffer | 100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol. |
