Application
Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.| Product Name | STEAP4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STEAP4 Antibody: TIARP, STAMP2, TNFAIP9, Metalloreductase STEAP4, Six-transmembrane epithelial antigen of prostate 4 |
| Product description | STEAP4 Antibody: The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.1) Korkmaz CG, Korkmaz KS, Kurys P, et al. Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer. Oncogene 2005; 24:4934-45. |
| Immunogen | STEAP4 antibody was raised against a 14 amino acid synthetic peptide from near the center of human STEAP4. The immunogen is located within amino acids 210 - 260 of STEAP4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| STEAP4 antibody can be used for detection of STEAP4 by Western blot at 0.5 - 1 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STEAP4 |
|---|---|
| Alternative Names | STEAP4 Antibody: TIARP STAMP2 TNFAIP9 Metalloreductase STEAP4 Six-transmembrane epithelial antigen of prostate 4 |
| Tissue Specificity | At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins. |
Application
Western blot analysis of STEAP4 in rat liver tissue lysate with STEAP4 antibody at (A) 0.5 and (B) 1 μg/mL.| Positive Control | 1) Cat. No. 1464 - Rat Liver Tissue Lysate |
|---|---|
| Application Notes | STEAP4 antibody can be used for detection of STEAP4 by Western blot at 0.5 - 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | STEAP4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | STEAP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
