| Product Name | Stearoyl-CoA Desaturase-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SCD1; Acyl-CoA Desaturase 1; Fatty Acid Desaturase 1 |
| Product description | Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage. |
| Immunogen | Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1. |
| Modification | Acetylated |
| Clonality | Polyclonal |
|---|---|
| Isotype | Cocktail |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WB:1:500~1:2000 |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Scd1 |
|---|---|
| Alternative Names | SCD1 Acyl-CoA Desaturase 1 Fatty Acid Desaturase 1 |
| Tissue Specificity | Recognizes mouse SCD1. Detects a band of ~41kDa by Western Blot. |
| Application Notes | WB:1:500~1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 6 months after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
