Stella Antibody: STELLA, STELLAR, Developmental pluripotency-associated protein 3, Stella-related protein
Product description
Stella Antibody: Stella was initially identified in primordial germ cells and pre-implantation embryos whose expression as a maternal factor is important in early embryonic development but is not required for germ cell specification in mice. In humans, Stella is thought to be a marker for pluripotency in embryonic stem (ES) cells as its expression is observed in primordial germ cells of both sexes and germ cell tumors but not in normal somatic tissues. However, in ES cell colonies, heterogeneous expression of Stella was seen in high throughput in situ hybridization assays, indicating that higher levels of complexity exist in otherwise thought to be undifferentiated ES cells. At least two distinct isoforms of Stella are known to exist.1) Sato M, Kimura T, Kurokawa K, et al. Identification of PGC7, a new gene expressed specifically in preimplatation embryos and germ cells. Mech. Dev.2002; 113:91-4.
Immunogen
Stella antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human Stella. The immunogen is located within the last 50 amino acids of Stella.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
Stella antibody can be used for detection of Stella by Western blot at 1 - 2 μg/mL.:
Western blot analysis of Stella in 293 cell lysate with Stella antibody at (A) 1 and (B) 2 μg/mL.
Positive Control
1) Cat. No. 1210 - HEK293 Cell Lysate
Application Notes
Stella antibody can be used for detection of Stella by Western blot at 1 - 2 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
Stella antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
Stella Antibody is supplied in PBS containing 0.02% sodium azide.