Application
Western blot analysis of STOX1 in human liver tissue lysate with STOX1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Product Name | STOX1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | STOX1 Antibody: PEE4, C10orf24, Storkhead-box protein 1, Winged-helix domain-containing protein |
| Product description | STOX1 Antibody: STOX1 (Storkhead box 1), also known as PEE4 or C10orf24, is a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. As a DNA-binding protein, STOX1 exists as three alternatively spliced isoforms, designated A, B and C, all of which localize to either the cytoplasm or the nucleus. Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4), also known as gestational proteinuric hypertension. STOX1 was also found to be functionally involved in late-onset Alzheimer's disease.1) Van Dijk M, van Bezu J, Chim SS, et al. Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. Nat. Genet. 2005; 37:514-9. |
| Immunogen | STOX1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human STOX1. The immunogen is located within amino acids 870 - 920 of STOX1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| STOX1 antibody can be used for detection of STOX1 by Western blot at 1 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STOX1 |
|---|---|
| Alternative Names | STOX1 Antibody: PEE4 C10orf24 Storkhead-box protein 1 Winged-helix domain-containing protein |
| Tissue Specificity | STOX1 antibody is human reactive. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. STOX1 antibody recognize the two longest isoforms. |
Application
Western blot analysis of STOX1 in human liver tissue lysate with STOX1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1304 - Human Liver Tissue Lysate |
|---|---|
| Application Notes | STOX1 antibody can be used for detection of STOX1 by Western blot at 1 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | STOX1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | STOX1 Antibody is supplied in PBS containing 0.02% sodium azide. |
