Sulfite oxidase is a homodimeric protein localized to the
intermembrane space of mitochondria. Each subunit contains a heme
domain and a molybdopterin-binding domain. The enzyme catalyzes the
oxidation of sulfite to sulfate, the final reaction in the
oxidative degradation of the sulfur amino acids cysteine and
methionine. Sulfite oxidase deficiency results in neurological
abnormalities which are often fatal at an early age. Alternative
splicing results in multiple transcript variants encoding identical
proteins.1) Rajapakshe, A., et al. Biochemistry 49(25):5154-5159(2010)
Immunogen
This SUOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-187 amino acids from the Central region of human SUOX.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.