This gene is located in the surfeit gene cluster, which is
comprised of very tightly linked housekeeping genes that do not
share sequence similarity. The encoded protein is a conserved
integral membrane protein containing multiple putative
transmembrane regions. In eukaryotic cells, protein transport
between the endoplasmic reticulum and Golgi compartments is
mediated in part by non-clathrin-coated vesicular coat proteins
(COPs). The specific function of this protein has not been
determined but its yeast homolog is directly required for packaging
glycosylated pro-alpha-factor into COPII vesicles. This gene uses
multiple polyadenylation sites, resulting in transcript length
variation. The existence of alternatively spliced transcript
variants has been suggested, but their validity has not been
determined.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This SURF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-237 amino acids from the C-terminal region of human SURF4.
Western blot analysis in mouse testis tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.