Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity1) "Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex. "Ito H., Atsuzawa K., Sudo K., Di Stefano P., Iwamoto I., Morishita R., Takei S., Semba R., Defilippi P., Asano T., Usuda N., Nagata K. J. Neurochem. 107:61-72 (2008) "A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation. "Tarpey P. S., Smith R., Pleasance E., et al. Nat. Genet. 41:535-543 (2009)
Immunogen
Synaptophysin antibody was raised against a peptide sequence around aa.305~309 (A-P-T-S-F) derived from Human Synaptophysin.