Application
Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.Application
Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 μg/mL.Application
Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 μg/mL.| Product Name | SYNGR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SYNGR1 Antibody: Synaptogyrin-1 |
| Product description | SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.1) Kedra D, Pan HQ, Seroussi E, et al. Characterization of the human synaptogyrin gene family. Hum. Genet.1998; 103:131-41. |
| Immunogen | SYNGR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human SYNGR1. The immunogen is located within amino acids 120 - 170 of SYNGR1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| SYNGR1 antibody can be used for detection of SYNGR1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SYNGR1 |
|---|---|
| Alternative Names | SYNGR1 Antibody: Synaptogyrin-1 |
Application
Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 μg/mL.
Application
Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | SYNGR1 antibody can be used for detection of SYNGR1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | SYNGR1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | SYNGR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
