The gene is a member of the inositol-polyphosphate
5-phosphatase family. The encoded protein interacts with the
ras-related C3 botulinum toxin substrate 1, which causes
translocation of the encoded protein to the plasma membrane where
it inhibits clathrin-mediated endocytosis. Alternative splicing
results in multiple transcript variants.1) Rikova, K., et al. Cell 131(6):1190-1203(2007)
Immunogen
This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.