This gene is a member of the tachykinin family of
neurotransmitter-encoding genes. Tachykinin proteins are cleaved
into small, secreted peptides that activate members of a family of
receptor proteins. The products of this gene preferentially
activate tachykinin receptor 1, and are thought to regulate
peripheral endocrine and paracrine functions including blood
pressure, the immune system, and endocrine gland secretion. The
products of this gene lack a dibasic cleavage site found in other
tachykinin proteins. Consequently, the nature of the cleavage
products generated in vivo remains to be determined. Multiple
transcript variants encoding different isoforms have been found for
this gene.1) Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
Immunogen
This TAC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TAC4.
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.