Application
Western blot analysis of TACI in K562 (A) and U937 (B) cell lysates with TACI antibody at 5 μg/mL.Application
Immunocytochemistry of TACI in K562 cells with TACI antibody at 2 μg/mL.| Product Name | TACI Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TACI Antibody: CVID, RYZN, TACI, CD267, CVID2, TNFRSF14B, Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor |
| Product description | TACI Antibody: Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-κB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.1) Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999;285:260-3 |
| Immunogen | TACI antibody was raised against a synthetic peptide mapping at the amino terminus of human TACI. The immunogen is located within the first 50 amino acids of TACI. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICCWB |
| TACI polyclonal antibody can be used for detection of TACI by Western blot at 5 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TNFRSF13B |
|---|---|
| Alternative Names | TACI Antibody: CVID RYZN TACI CD267 CVID2 TNFRSF14B Tumor necrosis factor receptor superfamily member 13B Transmembrane activator and CAML interactor |
| Sequence Similarities | 3) Cat. No. 17-004 - K-562 Cell Slide |
Application
Western blot analysis of TACI in K562 (A) and U937 (B) cell lysates with TACI antibody at 5 μg/mL.
Application
Immunocytochemistry of TACI in K562 cells with TACI antibody at 2 μg/mL.| Positive Control | 1) Cat. No. 1204 - K562 Cell Lysate |
|---|---|
| Application Notes | TACI polyclonal antibody can be used for detection of TACI by Western blot at 5 μg/mL. Antibody can also be used for immunocytochemistry starting at 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | TACI antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | TACI Antibody is supplied in PBS containing 0.02% sodium azide. |
